Looking for a bioinformatics expert?

What I have to offer:

• A balanced background in both biology (BSc) and computer science (BCS)
• Soon to be completed PhD
  
• Extensive research experience in bioinformatics, genomics, phylogenetics/phylogenomics, evolution, and bacteria pathogenesis
• Some previous research experience in medical imaging, ontology development, and metagenomics
  
• An impressive publishing record (7 papers, 3 first authors, 2 more first authors under review)
  
• Solid computational skills including Perl programming, database design (MySQL), parallel programming, and web design (PHP & JavaScript)
• Good communication and social skills
  
• More information

What I am looking for:

• Post-doc or job (academic or industrial)
• Preferably, a position where I have some significant manager or leadership responsibilities
  
• Geographically interested in north eastern parts of North America (Ottawa down to New York), but would entertain positions elsewhere in N.A.

I didn't put any limitations on research interests, since I am open to many areas. However, anything having to due with the human microbiome project, human-bacteria interactions, or metagenomics would be of particular interest.

Please email me if you are interested or if you have suggestions on some good openings.

Review of Arrowhead Conference

I was hoping to write this during the conference, but every talk I went to was really interesting and I ended up not using that time for blogging. However, there is at least one talk that I wanted to mention before I forgot to much.

I thought the most interesting talk was from Kim Lewis, who describes "persistor cells" as those bacteria that lay dormant in a population. These persistors are resistant to antibiotics because they are essentially shut down and passivly allow antibiotics to simply wash over them as opposed to normal bacteria cells that actively block or pump out antibiotics. Lewis also showed that late samples taken from cystic fibrosis patients had high levels of persistor cells. Kim then discussed unculturable bacteria (of which 99% of bacteria are) and suggested that when plated on media that these are actually dormant and not dead. To support this Kim showed that by innoculating an unculturable sample with E.coli caused growth of an unculturable strain around the E.coli spot. He later found a mutant that did not cause the effect and identified the key gene to be a sideophore. Lewis ends with this little tidbit, "Dormancy is the default mode of bacterial life". I find this really interesting because it suggests that most bacteria depend on a few bacteria to signal when their surrondings are optimal for growth.

There are a couple of more talks that I hope to blog about in the next day or two.

Fecal Transplant

I couldn't pass up blogging about this recent news article that discusses how transplanting feces to patients with C. difficile can cure their illness. I think it is a great example of how important and natural a balanced microfauna is to human health. I think in a short time we will start to see "probiotic" (I really hate that word) medical treatments on the rise.